Starting a business in Spain in 2025 will be a strategic decision influenced by economic trends and local opportunities. The selected cities stand out for their ability to adapt to changes, innovation, and the resources they offer to entrepreneurs. Here are the 10 best options to start your business this year.

 

1. Madrid

The capital is the economic epicenter of Spain and a privileged place to start a business.

Key advantages

  • Consolidated business ecosystem with access to investors, accelerators, and large corporations.
  • International connectivity through its Adolfo Suárez Madrid-Barajas airport.
  • Diversity of key sectors such as technology, finance, commerce, and services.
  • Extensive cultural and leisure offerings that attract talent from around the world.

 

2. Barcelona

An international reference in technology and innovation.

Key advantages

  • Major digital and technological hub in Europe, especially in sectors such as e-commerce, fintech, and biotechnology.
  • Strong entrepreneurial ecosystem, with events like the Mobile World Congress and the Smart City Expo.
  • International appeal for its quality of life, Mediterranean climate, and cosmopolitan atmosphere.
  • Headquarters of important startups and multinational companies.

 

3. Valencia

The Mediterranean city has gained prominence as a destination for entrepreneurs.

Key advantages

  • Lower cost of living compared to other major cities, with a high quality of life.
  • Districts like Marina de Empresas promote entrepreneurship and innovation.
  • Collaborative and ever-growing entrepreneurial community.
  • Strategic location and excellent connectivity with the rest of Spain and Europe.

 

4. Málaga

The “City of the Sun” stands out for its commitment to technology and sustainability.

Key advantages

  • Andalusia Technology Park (PTA), home to national and international tech companies.
  • Exceptional climate that promotes a balanced lifestyle and attracts international talent.
  • Growing foreign investment in sectors such as technology, tourism, and renewable energy.
  • Vibrant cultural ecosystem that complements its business appeal.

 

5. Bilbao

The heart of the Basque Country is a hub of industrial and sustainable innovation.

Key advantages

  • Focus on Industry 4.0, green technologies, and renewable energy.
  • Support programs like those from Spri, offering grants and business advice.
  • Strategic location with top-notch port and logistics connections.
  • Urban transformation that blends modernity and history, attracting foreign investment.

 

6. Sevilla

The Andalusian capital combines history, culture, and business opportunities.

Key advantages

  • Emerging tech startup ecosystem, particularly in renewable energy and tourism.
  • Institutional support through local accelerators and innovation programs.
  • Modern infrastructure and an airport with good national and international connections.
  • Growing market that offers great opportunities for entrepreneurs.

 

7. Zaragoza

Una ubicación estratégica entre Madrid, Barcelona y Bilbao.

Ventajas clave

  • Referente logístico y de transporte en España, con plataformas como PLAZA (Plataforma Logística de Zaragoza).
  • Costes operativos más bajos en comparación con las grandes ciudades.
  • Talento procedente de su potente red universitaria y centros de investigación.
  • Desarrollo en sectores clave como la industria agroalimentaria y las energías renovables.

 

8. Palma de Mallorca

An ideal destination for businesses related to tourism and sustainability.

Key advantages:

  • Economy focused on quality tourism and marine technology, with innovation projects in these sectors.
  • Local policies supporting entrepreneurship that promote the creation of businesses.
  • International environment thanks to its appeal as a tourist destination.
  • Initiatives in circular economy and sustainability.

 

9. Alicante

A city on the rise thanks to the Digital District of the Valencian Community.

Key advantages

  • Expanding technological ecosystem, with a special focus on emerging technologies.
  • Excellent quality of life, with good weather and competitive costs.
  • Quick connection to Madrid and Barcelona thanks to the high-speed train.
  • Growing attractiveness for international startups and tech companies.

 

10. Granada

A knowledge center driven by its prestigious university.

Key advantages

  • Specialization in biomedicine, artificial intelligence, and data technology.
  • Accessible cost of living that facilitates the attraction of young talent.
  • Growing support for entrepreneurship in technology through incubators and accelerators.
  • Cultural and historical richness that complements its appeal as an entrepreneurial city.

Each city has its own business DNA. Choosing the right location for your business will depend on your goals, the sector you operate in, and the specific needs of your project.

 

✅​ Establish your company with confidence

Don’t know what steps to follow to create a company and meet all the obligations?

Don’t worry, at Adlanter, we know well what your concerns and needs are. Contact us!

We will take care of all the paperwork related to the company formation, from drafting the articles of incorporation to registering the tax activity of the entity.

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